The state of Pennsylvania is home to some of the leading hospitals in the US. The best hospitals in Pennsylvania include the Hospital of the University of Pennsylvania (HUP) in Philadelphia which was recognized by the US News & World Report as one of only 19 hospitals all over the country that showed a wide breadth of excellent health care services, thereby gaining a spot in the list of Best Hospitals Honor Roll. The Lehigh Valley Hospital in Allentown is another one of the best hospitals in Pennsylvania. This hospital was also listed by the US News as one of America's best hospitals, achieving high adult specialty rankings in the fields of Gastrointestinal Disorders, Geriatric Care, and Heart and Heart Surgery.

Aside from outstanding specializations in the adult category, Pennsylvania also provides first-rate care and treatment in the pediatrics division with The Children's Hospital of Philadelphia. Founded in 1855, this hospital is recognized as the first hospital exclusive for children's care and is not only a leading hospice for kids today, but a top-notch research facility as well.